OptumRx MAC Appeal Submission Guide and FAQ
Note: See state specific additional requirements below for Arkansas, Delaware, Florida, Idaho, Kansas, Louisiana, Mississippi, New Mexico, Oklahoma, Oregon, South Carolina, Tennessee, and Washington.
Appeals must be submitted within 30 days of the claim fill date or within such time period as may be required by applicable state law. Appeals exceeding the allowable submission period will NOT be reviewed. Please refer back to the pharmacy manual for information specific to your state.
Please submit all MAC Appeal requests using the approved OptumRx spreadsheet via the Pharmacy Portal using your OptumID. If you do not have an OptumID you may register to create one here:
Create OptumID Here
Any other form of appeal submission will not be accepted for review. Excel file for Appeals can be found here:
MAC Appeal Detail must be filled out completely unless noted as "Optional". Submissions with missing information will be invalid and excluded from review.
All reviews of any individual claim from a pharmacy are final and will NOT be reviewed again.
Alternate and/or reference National Drug Code information provided on denied appeal responses, where applicable and required by law, represent products identified by OptumRx as being available from a national wholesaler operating in your state at or below the maximum allowable cost as determined by OptumRx.
OptumRx MAC review process does not provide clinical advice nor direction for product substitutions. Please refer to your state substitution laws.
Required Information
The following fields must be filled out in order to be processed (marked as REQUIRED on MAC Appeal form template):
-BIN (formatted to 6 digits)
-NCPDP (formatted to 7 digits)
- Rx Number (formatted to 12 digits)
- Filled Date (formatted mm/dd/yyyy)
-Reason for Review (drop down on template)
- Notes (as required per State)
- Provider per unit drug acquisition cost 1 (as required per State)
- Net Purchase Price of Drug (as required per State)
- Total Reimbursement (as required per State)
- Drug Name (as required per State)
- Drug Strength (as required per State)
- Attestation to interest of shares in Pharmaceutical Wholesale Group Purchasing Organization or Vendor (as required per State)
**NEW** State specific requirements per State MAC Legislation
- Arkansas Providers
Consistent with Ark. Code. Ann. § 17-92-507, where applicable, Arkansas providers are required to include pharmacy acquisition cost* with their appeal submission as outlined below. Please enter information into column “K” of the OptumRx MAC Appeal Submission Template.
If the required pharmacy per unit acquisition cost* information is not submitted at time of appeal, OptumRx will be unable to review and resolve the appeal and will request resubmission of the appeal with the required information for reprocessing.
This is in accordance with Arkansas Insurance Department Bulletin NO. 5-2022, effective June 1, 2022, requiring PBMs allow providers to transmit their invoice cost information with their appeal submission. Providers can submit their invoice via email to MAC@Optum.com. Providers are required to submit with the following information;
Email Subject Line: File name and submission date of the appeal.
Body of the email: Rx number, fill date, and the NDC number.
- Delaware Providers
In accordance with State of Delaware Legislation, effective October 26, 2021, where applicable, Delaware providers can now provide per unit acquisition cost* information at the time of appeal. In order to review, provider will need to use the MAC appeal form and enter a per unit acquisition cost information into column “K” of the OptumRx MAC Appeal Submission Template.
If the required drug acquisition cost information is not submitted at time of appeal, OptumRx will be unable to review and resolve the MAC Appeal and will request resubmission of the MAC Appeal with the required information for reprocessing.
- Florida Providers
In accordance with State of Florida Legislation SB1550, effective January 01, 2024, where applicable, Florida providers can now provide acquisition cost information at the time of appeal. In order to review, provider will need to use the MAC appeal form and enter a per unit acquisition cost information into column “K” of the OptumRx MAC Appeal Submission Template.
If the required drug acquisition cost information is not submitted at time of appeal, OptumRx will be unable to review and resolve the MAC Appeal and will request resubmission of the MAC Appeal with the required information for reprocessing.
- Idaho Providers
In accordance with State of Idaho Legislation HB 596, effective January 01, 2025, where applicable, Idaho providers can now provide per unit acquisition cost* information at the time of an appeal. In order to review, provider will need to use the MAC appeal form and enter a per unit acquisition cost information into column “K” of the OptumRx MAC Appeal Submission Template.
If the required drug acquisition cost information is not submitted at time of appeal, OptumRx will be unable to review and resolve the MAC Appeal and will request resubmission of the MAC Appeal with the required information for reprocessing.
- Kansas Providers
In accordance with State of Kansas Senate Bill 28, effective July 1, 2022, where applicable, Kansas Providers have the option to include their total reimbursement amount* information with their appeal submission from its contracted supplier as outlined below. Please enter information into column “N” of the OptumRx MAC Appeal Submission Template.
- Louisiana Providers
In accordance with State of Louisiana S444 effective January 1, 2025, where applicable, Louisiana providers can provide acquisition cost * information at the time of an appeal. In order to review, provider will need to use the MAC appeal form and enter a per unit acquisition cost information into column “K” of the OptumRx MAC Appeal Submission Template.
If the required drug acquisition cost information is not submitted at time of appeal, OptumRx will be unable to to review and resolve the MAC Appeal and request resubmission of the MAC Appeal with the required information for reprocessing.
In addition, the provider must attest that a pharmacy does NOT own more than 5 shares or 5% interest in a pharmaceutical wholesale group purchasing organization or vendor of any covered drug, device or service. So, if a pharmacy does own more than 5 shares or 5% interest in a pharmaceutical wholesale group purchasing organization or vendor of any covered drug, device or service, then the OptumRx does NOT need to reimburse the pharmacy at the pharmacy’s acquisition cost. That information will be entered on the MAC appeal form under column “Q”.
- Mississippi Providers
In accordance with State of Mississippi House Bill 708, effective January 01, 2021, where applicable, Mississippi providers are required to include the provider’s per unit drug acquisition cost* information with their appeal submission from its contracted supplier as outlined below. Please enter information into column “K” of the OptumRx MAC Appeal Submission Template.
If the required drug acquisition cost information is not submitted at time of appeal, OptumRx will be unable to review and resolve the MAC Appeal and will request resubmission of the MAC Appeal with the required information for reprocessing.
Mississippi providers may submit a request for a secondary review of a previously denied MAC appeal when the provider is unable to acquire the OptumRx referenced product from the OptumRx referenced Wholesaler at or below MAC. In order to request a secondary review, provider will need to use the MAC appeal form and select “Mississippi - Wholesaler unavailability” under the “Reason for Review” column indicating you are unable to acquire the referenced product from the referenced wholesaler on the originally denied appeal. You will also be required to include your drug acquisition cost* information as outlined below. Please enter your drug acquisition cost information into column “K” of the OptumRx MAC Appeal Submission Template. If the drug acquisition cost information and “Mississippi – Wholesaler unavailability” reason code are not submitted at the time of your secondary review request, OptumRx will not have the necessary information to conduct a secondary review. The allowable period for a secondary review request is 30 business days following our initial denial.
- New Mexico Providers
In accordance with New Mexico Legislation NMAC 13.10.30, effective March 1, 2022, where applicable, New Mexico Providers are now required to include their Net Purchase Price of Drug (column M), Total Reimbursement (column N), Drug Name (column O), and Drug Strength (column P). In order to ensure prompt and accurate review of your appeal this information must be provided on the MAC appeal form at time of submission.
- Oklahoma Providers
In accordance with State of Oklahoma Legislation, effective May 04, 2021, where applicable, Oklahoma providers can now provide per unit acquisition cost* information at the time of appeal. In order to review, provider will need to use the MAC appeal form and enter a per unit acquisition cost information into column “K” of the OptumRx MAC Appeal Submission Template.
If the required drug acquisition cost information is not submitted at time of appeal, OptumRx will be unable to review and resolve the MAC Appeal and will request resubmission of the MAC Appeal with the required information for reprocessing.
- Oregon Providers
In accordance with State of Oregon Legislation 45414, effective January 01, 2021, where applicable, Oregon providers can now provide cost information based on generally available for purchase products. In order to review, provider will need to use the MAC appeal form and select “Oregon Pharmacy – Unable to acquire product at or below specified amount for 3 month or less supply” under the “Reason for Review” column. When selecting this reason code, the pharmacy must submit the provider’s per unit drug acquisition cost* information with their appeal submission from its contracted supplier as outlined below. Please enter information into column “K” of the OptumRx MAC Appeal Submission Template.
If the required drug acquisition cost information is not submitted at time of appeal, OptumRx will be unable to review and resolve the MAC Appeal, and will request resubmission of the MAC Appeal with the required information for reprocessing.
- South Carolina Providers
Network Pharmacy Provider may request an external review of a denied MAC Appeal if the Network Pharmacy Provider believes Administrator erred in denying the MAC Appeal which resulted in a reimbursement inconsistent with the requirements of S.C. Code Ann. Section 38-71-2240, effective January 1, 2024. Network Pharmacy Provider's request for an external review must comply with the requirements of S.C. Code Regs. 69-77 Section VIII. Network Pharmacy Provider may contact the South Carolina Department of Insurance at 1201 Main Street, Suite 1000, Columbia, SC 29201, (803) 734-0398, for assistance.
- Tennessee Providers
Consistent with T.C.A. § 56-7-3206(c)(2)(B)(ii) and TN Rule 0780-01-95-.05, OptumRx’s MAC appeals process may be used for non-MAC related reimbursement appeals, and all prescription drugs or devices for which a provider alleges it did not receive its actual cost. Providers must file appeals within seven (7) business days of its submission of the initial claim. Administrator will investigate and resolve the appeal within seven (7) business days after receipt of the completed MAC Appeal Submission Template, or the Tennessee Standard Pharmacy Reimbursement Appeal Form. The timeline for final determination of the initial appeal will begin once Administrator has received all of the required information including: 1) a complete version of the OptumRx MAC Appeal Submission Template or Tennessee Standard Pharmacy Reimbursement Appeal Form; and 2) certification from the Provider that it has provided all invoices or other records demonstrating the Provider’s actual costs for the drug or medical product or device at issue, including all discounts, price concessions, rebates or other reductions received as of the date that the Provider filed its appeal. If a Provider’s appeal does not contain all information required under TN Rule 0780-01095-.05(2), Administrator will accept the incomplete appeal and hold it open pending receipt of additional information from Provider. Within five (5) business days of receipt of an incomplete appeal, Administrator will notify Provider of the information needed to complete Administrator’s review the appeal. If the Provider provides the requested information, within five (5) business days of receipt of the Administrator’s notice outlining the requested information, Administrator’s timeline to make final determination shall start. If the Provider fails to provide the requested information within five (5) business days of receipt of Administrator’s notice, Administrator will deny Provider’s appeal. If Administrator fails to comply with the timing and notice requirements under applicable law, the appeal shall be resolved in favor of the Provider.
Tennessee providers are required to include pharmacy per unit acquisition cost* with their appeal submission as outlined below. If a Provider is using Optum Rx’s MAC Appeal Submission Template to submit an appeal, please complete the template and enter acquisition cost information into Column "K". If the required provider acquisition cost information is not submitted at time of appeal, OptumRx will be unable to review and resolve the appeal and will request resubmission of the appeal with the required information for reprocessing, as more fully described above. Tennessee providers are required to include name of wholesaler or manufacturer, as applicable, from which the pharmacy purchased the drug or medical product or device at issue, please place that information in the Column “J” under Notes. A copy of the Provider’s invoice demonstrating the pharmacies actual cost as of the date of the filing can be emailed to MAC@optum.com.
Providers are encouraged, but not required to fill out the Optum Rx MAC Appeal Submission Template and submit appeals through the Optum Rx automated system. Optum Rx will accept the Tennessee Standard Pharmacy Reimbursement Appeal Form via email at MAC@optum.com. If a provider chooses to use the Tennessee Standard Pharmacy Reimbursement Appeal Form, completed forms can be emailed to MAC@Optum.com with the email subject “TN Appeal – NCPDP (please enter your pharmacy number)”. Please contact 1-800-613-3591 Ext. 9 or MAC@Optum.com with any questions. With each claim submission, Providers should include their wholesaler’s name under the “Narrative Message” field, within the submitted pharmacy menu screen.
- Washington Providers
Washington providers are required to include the provider’s per unit drug acquisition cost* information with their appeal submission from its contracted supplier as outlined below. Please enter information into column “K” of the OptumRx MAC Appeal Submission Template.
If the required drug acquisition cost information is not submitted at time of appeal, OptumRx will be unable to review and resolve the MAC Appeal, and will request resubmission of the MAC Appeal with the required information for reprocessing.
*Submitted provider per unit drug acquisition cost information must be the Provider’s lowest per unit acquisition cost for the drug dispensed on the appealed claim during the time period of the claim. The per unit drug acquisition cost you provide must be net of any rebates and discounts from your supplier or the manufacturer and must be limited to the drug ingredient cost, excluding any pharmacy service fees. OptumRx reserves the right to request supporting documentation, including, but not limited to, supplier and manufacturer invoices. Drug acquisition cost and related information submitted to OptumRx is subject to audit and validation via an invoice request.
Formatting
Any formatting errors will cause delays in appeal review. The details on errors will be sent in the Resolution Response, review original file submitted and resubmit with corrections. Please follow the formatting specifications in the headings so your appeals can be processed as in a timely manner.
Following Fields must reflect information from the Drop-down Menu as follows:
Reason for Review
Compound Y/N
-Y (select Y to indicate a compound)
-N (select N to indicate a non-compound)
-If more than one ingredient is to be reviewed fill out individual lines for each NDC.
Common Formatting Errors
- Not including leading zeros in BIN, NCPDP, RX#, PCN, or NDC (example NCPDP 412345 instead of 0412345).
- Incorrect or missing date of fill (example 3/10/2103 instead of 3/10/2013).
- Changing the format to custom to give the appearance of leading zeros. Numbers must be in text format to be processed.
- Missing any of the required fields.
- Adding letters to BIN numbers (example 012353A instead of 012353).
- Entering NDC with dashes (example 00012-3456-78 instead of 00012345678).
- If you have any questions regarding this process or any concerns, please refer to the Pharmacy Manual for contact information.
- Any resolved appeals returned with the status of:
- Client MAC CIG, are considered to be custom MAC lists maintained by Cigna through their direct contract with pharmacies. Any questions regarding the Cigna Client MAC pricing claims should be addressed to MACInquiry@cigna.com.
- For all Georgia Medicaid MAC appeals submitted, please refer online under www.mmis.georgia.gov → Pharmacy → Pricing List for a complete list of GMAC prices, including changes
- Any resolved appeals with the status of Claim Paid according to the effective rate contracted, implies that the claim paid according to the Effective Rate contracting, providing increased pricing transparency and predictability of rate trends. Guarantees offer PSAO with guardrails to protect the financial interest of its affiliated pharmacies while ensuring access to OptumRx networks.
Resolution Responses and definitions:
| Appeal Reason Description (Status) | Definitions | Determination |
| Approved Pricing Reconciliation | OptumRx has reviewed and approved appeal. Payment will be issued on next payment cycle for amount due as a result of adjusted reimbursement. (R&R not required) | Approved |
| Increase | OptumRx has reviewed and approved appeal. Pharmacy may R&R claim. | Approved |
| Increase – Reimbursement Adjustment in Progress | OptumRx has reviewed and approved appeal. Payment will be issued on next payment cycle for amount due as a result of adjusted reimbursement. (R&R not required) | Approved |
| Acq not Provided | Per unit drug cost was not originally submitted in column “K” on the OptumRx MAC Appeals Template | Denied |
Missing Required Acquisition Cost | Per unit drug cost was not originally submitted in column “K” on the OptumRx MAC Appeals Template | Denied |
| Appeal window exceeded | Appeal exceeds allowable submission period | Denied |
| AWP | Claim paid at the contracted AWP rate | Denied |
| Claim not found | Claim could not be found within Optum given the supplied criteria. | Denied |
| Claim Not Found - Unknown RxNumber | Claim could not be found within Optum given the supplied criteria. (review original submission and common formatting errors) | Denied |
| Claim Paid according to effective rate contracted | Claim Paid at the Contracted Rate | Denied |
| Claim Paid at Provider submitted U & C | Claim Paid at Submitted Usual and Customary cost | Denied |
| Client MAC | Contact client to review claim | Denied |
| Duplicate/Duplicate Appeal | Duplicate Appeal Submission | Denied |
| FUL | Claim Paid at Federal Upper Limit | Denied |
| No change | Appeal denied. MAC price accurate | Denied |
| No Change MAC Price Valid | Appeal denied. MAC price accurate | Denied |
| Non-MAC claim | Claim could not be found within Optum given the supplied criteria. | Denied |
| Non-OptumRx claim | Claim could not be found within Optum given the supplied criteria. | Denied |
| Non-paid claim | Rejected / X (Reversed) /Claim Reversed. Appeal as submitted is for a reversed or rejected claim. Can only appeal paid claims. | Denied |
| Not Found | Claim could not be found within Optum given the supplied criteria. | Denied |
| Paid at AAC | Claim paid at the contracted AAC rate | Denied |
| Paid at AWP/WAC | Claim paid at the contracted AWP rate/paid at WAC pricing | Denied |
| Paid at Contracted Rate | Claim Paid at the Contracted Rate | Denied |
| Paid at FUL | Claim Paid at Federal Upper Limit | Denied |
| Paid at NADAC | Claim paid at NADAC pricing | Denied |
| Paid at pharmacy submitted | Claim Paid at Submitted Usual and Customary cost | Denied |
| Paid at SD | Claim Paid at Submitted Usual and Customary cost | Denied |
| Paid at SM | Claim Paid at the Contracted Rate | Denied |
| Paid at U&C | Claim Paid at Submitted Usual and Customary cost | Denied |
| Paid at WAC | Claim paid at WAC pricing | Denied |
| Paid at zero | Non MAC Claim | Denied |
| Pending Review | Appeal is under review | Denied |
| Previous Change | MAC price increased | Denied |
| Provider Reimbursed >= Provided Submitted | Provider Per Unit submitted on appeal was lower than original Per Unit paid on claim. No change. | Denied |
| Too Old | Appeal exceeds allowable submission period | Denied |
| No Invoice Provided Upon Request | Request was sent for Invoice, due to per unit clarification needed. There was no response and could not proceed with processing the appeal. | Denied |
| Unknown BIN | Claim could not be found within Optum given the supplied criteria. (review original submission and common formatting errors) | Denied |
| Unknown Date of Service | Claim could not be found within Optum given the supplied criteria. | Denied |
| Unknown NCDPD ID | Claim could not be found within Optum given the supplied criteria. (review original submission and common formatting errors) | Denied |
| Unknown NDC | Claim could not be found within Optum given the supplied criteria. | Denied |
| Unknown RxNumber | Claim could not be found within Optum given the supplied criteria. (review original submission and common formatting errors) | Denied |
| WAC | Claim paid at WAC pricing | Denied |
| Conflict of Interest | LA Legislative requirement, if Y is entered on the MAC appeal form in column “Q” | Denied |